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[He] is a pediatric cognitive neuroscientist. His research focuses on the neural basis of cognitive impairments seen in genetic disorders that produce mental retardation, developmental disability and psychopathology. Building on his influential theory of the foundations of numerical competence, [he] investigates how dysfunction in specific neurocognitive processing systems, such as attention and spatial cognition, can generate a range of cognitive and behavioral impairments. His goal is to develop remedial intervention programs that will minimize such disability. [His] current projects center on studies of visuospatial and numerical cognition in children with chromosome 22q11.2 deletion syndrome, also known as DiGeorge and VeloCardioFacial syndrome. He is also engaged in similar studies of children with Fragile X, Williams, and Turner syndromes. Besides cognitive processing analyses and psychometric testing, [he] uses cutting edge neuroimaging methods, such as functional magnetic resonance imaging (fMRI), Voxel Based Morphometrics, and Diffusion Tensor Fiber Tracking in order to study the structure, function and connective patterns in the developing brain.